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5-Bromo-4-chloro-3-indolyl acetate Is Used To Detect Urinary Tract Infections, BV And Other Diseases

2020-05-20 来源:转载自第三方

5-Bromo-4-chloro-3-indolyl acetate is a superior product of Yacoo Science. It is an in vitro diagnostic reagent, and its CAS number is 3252-36-6. As a substrate for leukocyte esterase, 5-Bromo-4-chloro-3-indolyl acetate is often used for the detection of bacterial vaginitis (BV) and urinary tract infections.

Urinary tract infections and BV not only harm women's health, but also have a great impact on psychology and life. 

Leukocyte esterases are commonly used clinically for the determination of leukocytes in specimens. Positive leukocyte esterases can be used for the diagnosis of urinary tract infections, such as nephritis and urinary tract infections. In addition, the measurement of leukocyte esterase activity is a routine item of BV examination.

When an inflammatory reaction occurs in the body, due to the chemotaxis of neutrophils, it accumulates in the inflammatory lesions and releases a large amount of leukocyte esterase. Therefore, the detection of vaginal leukocyte esterase content can reflect the degree of vaginal inflammation, and it is also an evaluation of the cleanness of vaginal secretions An important indicator of the degree and degree of vaginal mucosal damage. 

At present, the detection of leukocyte esterase mainly uses inflammation test paper, the principle of which is to spray 5-Bromo-4-chloro-3-indolyl acetate on the test paper.

If there is inflammation, the leukocyte esterase activity in urine and vaginal secretions is abnormal, which will hydrolyze 5-bromo-4-chloro-3-indolyl acetate, releasing bromoindolyl, which is in Under conditions, it is blue, and the color depth is proportional to the activity of leukocyte esterase.

It can be seen that 5-Bromo-4-chloro-3-indolyl acetate has important value as an in vitro diagnostic reagent.

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