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Why Is β-nicotinamide mononucleotide (NMN) Anti-aging?

2020-06-23 来源:亚科官网

β-nicotinamide mononucleotide(NMN) has the effect of delaying aging, and is called the "miracle medicine" for prolonging life. It can not only reduce the typical aging symptoms, but also alleviate a series of health problems caused by the aging of the body, such as Vascular disorders, Alzheimer's disease, etc. So why is  β-nicotinamide mononucleotide anti-aging?

The anti-aging effect of β-nicotinamide mononucleotide should start from its relationship with coenzyme I (NAD). The β-nicotinamide mononucleotide is a synthetic substrate of coenzyme I, and becomes a coenzyme I after being adenylated by the nicotinamide nucleotide adenosine transferase.

Coenzyme I is known as nicotinamide adenine dinucleoside acid or nicotine diphosphate. It has two states, oxidized (NAD+) and reduced (NADH) in mammals. It is an important coenzyme in the redox reaction of the human body and participates in cells. Various physiological activities such as material metabolism, energy synthesis, and cellular DNA repair have an important role in the body's immune ability.

The concentration of coenzyme I in the body determines the process and degree of cell aging. Under healthy conditions, the concentration of coenzyme I in the human body is stable, which can maintain the normal function of various cells, but with the increase of age, the content of coenzyme I in the human body Gradually decreasing, the concentration level will decrease the activity of mitochondria, impair the ability of cells to produce energy, accelerate the aging process of mitochondria, cells and even the whole body, which is why humans will age.

The β-nicotinamide mononucleotide is a precursor of coenzyme I, and studies have shown that β-nicotinamide mononucleotide is considered to be the most effective way to supplement Coenzyme I. The β-nicotinamide mononucleotide can be absorbed intact through the digestive system, and it can enter the blood within 2-3 minutes, which can quickly increase the level of coenzyme I in the blood, liver and other organs, thereby delaying aging.